There are products, available only through a doctor, that can provide dramatic and visible changes to your skin. Of course, don’t expect miracles.
Retinoids (Renova, Avage), or Vitamin A derivatives are the only proven topical prescription remedy for wrinkles. According to the definition in wikipedia ” Retinoids have many important and diverse functions throughout the body including roles in vision, regulation of cell proliferation and differentiation, growth of bone tissue, immune function, and activation of tumor supressor genes.
With the wrinkle improvement come some side effects though. They can be inherently irritating. New users can expect their skin to be red, itchy, and peeling for a few weeks. Eventually the irritation clears up but some people experience persistent dry skin. Retinoid-treated skin also gets red more quickly in the sun.